Eppendorf BioFlo 320

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Summary

Successful exploitation of this vulnerability could allow an attacker to gain full access to functionality and data with the bioreactor.

The following versions of Eppendorf BioFlo 320 are affected:

  • BioFlo 320 Bioreactor vers:all/*
CVSS Vendor Equipment Vulnerabilities
v3 9.8 Eppendorf Eppendorf BioFlo 320 Use of Hard-coded Password

Background

  • Critical Infrastructure Sectors: Healthcare and Public Health
  • Countries/Areas Deployed: Worldwide
  • Company Headquarters Location: Germany

Vulnerabilities

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CVE-2026-7251

The affected product is vulnerable to due to VNC server using a hard-coded password. If a remote attacker knows the network address of any BioFlo 320 model with remote access enabled, they can gain full control of the user interface by using this password. Once connected, the attacker would have full access to all control panel features for the BioFlo 320. VNC traffic is not encrypted.

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Affected Products

Eppendorf BioFlo 320
Vendor:
Eppendorf
Product Version:
Eppendorf BioFlo 320 Bioreactor: vers:all/*
Product Status:
known_affected
Remediations

Mitigation
Eppendorf has released a software update that permanently removes VNC access from the controller. Users should download and apply this update from: https://www.eppendorf.com/software-downloads.
https://www.eppendorf.com/software-downloads

Mitigation
All affected BioFlo 320 systems always shipped with Virtual Network Computing (VNC) disabled by default, and VNC can only be enabled locally at the tower. Eppendorf has removed VNC configuration information from all current documentation, so it no longer appears in BioFlo 320 Operating Manuals.

Mitigation
Eppendorf recommends user do the following:
Verify that VNC is disabled on the controller
Enable security so that only Admin and Supervisor roles can change VNC settings
Install Version 5.0 Software as soon as possible

Relevant CWE: CWE-259 Use of Hard-coded Password


Metrics

CVSS Version Base Score Base Severity Vector String
3.1 9.8 CRITICAL CVSS:3.1/AV:N/AC:L/PR:N/UI:N/S:U/C:H/I:H/A:H

Acknowledgments

  • BIO-ISAC reported this vulnerability to CISA

Legal Notice and Terms of Use

This product is provided subject to this Notification (https://www.cisa.gov/notification) and this Privacy & Use policy (https://www.cisa.gov/privacy-policy).


Recommended Practices

CISA recommends users take defensive measures to minimize the risk of exploitation of this vulnerability.

Minimize network exposure for all control system devices and/or systems, ensuring they are not accessible from the internet.

Locate control system networks and remote devices behind firewalls and isolating them from business networks.

When remote access is required, use more secure methods, such as Virtual Private Networks (VPNs), recognizing VPNs may have vulnerabilities and should be updated to the most current version available. Also recognize VPN is only as secure as the connected devices.

CISA reminds organizations to perform proper impact analysis and risk assessment prior to deploying defensive measures.

CISA also provides a section for control systems security recommended practices o

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